RSS Mitochondrial

  • Emerging Therapies for Mitochondrial Disorders June 4, 2023
    Future pharmaceutical development focusing on disease-specific or patient-specific molecular targets aimed at boosting residual mitochondrial function is likely to be more successful than previous ...
  • Family Resilience of Children with Neurodevelopmental Disorders June 3, 2023
    Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the ...
  • What is employee resilience May 31, 2023
    In order to deal with these obstacles, many organisations have turned to employee resilience to weather the storm. Studies have found that managers respond to business turbulence by emphasising ...
  • What is cyber resilience? May 28, 2023
    Cyber resilience is the ability to prevent, withstand, adapt, or recover from various types of cyber-attacks on the data of an individual or an organization. In today’s digital landscape, ...
  • Mitochondrial proteins articles from across Nature Portfolio May 17, 2023
    Mitochondrial proteins are proteins that reside within the mitochondria of cells, including within the cristae of the inner mitochondrial membrane. Mitochondrial proteins are generally involved in ...
  • A health systems resilience research agenda: moving from concept to practice January 25, 2023
    Health system resilience, known as the ability for health systems to absorb, adapt or transform to maintain essential functions when stressed or shocked, has quickly gained popularity following shocks ...
  • Mitochondrial morphogenesis April 25, 2022
    Mitochondrial function relies on the complex mitochondrial shape, membrane ultrastructure and dynamics, which abnormalities lead to organelle dysfunction and eventually cell death. Our work focus on ...
  • The Resilience Quotient April 15, 2021
    How we communicated. How we lived. Through it all, confronted with so many challenges, people showed a remarkable spirit of resilience. Individuals, families, and organizations displayed an inspiring ...
  • Mitochondrial Medicine February 25, 2021
    The mission of Wartiovaara lab is to understand the molecular background of mitochondrial disorders, and use that knowledge to develop diagnosis and therapy. Mitochondrial dysfunction has shown out to ...
  • Resilience & Coping August 13, 2020
    Can’t cope? Overwhelmed? Stressed? We all have trouble coping at some points in life. We don’t get the promotion we hoped for; our relationship breaks [...] ...


SAFE G: Empowering Resilient Communities


Mission. To empower local communities to design immediate and effective SAFE G solutions that implement optical fiber wired to the home and office. Local taxpayers and ratepayers are entitled to this alternative to wireless, because they have already paid for it. Please see: Irregulators v. FCC.

5G/AI/Internet of Things Juggernaut presents an imminent threat. The harms to our community’s physical and mental health, the local environment, violations of citizen’s rights to due process, property, and personal privacy are foreseeable and preventable. The threat is especially dangerous to our children, elderly people, those with special sensitivities, disabled persons with chronic illnesses, caregivers, and our economically disadvantaged and minority communities that have no escape in their homes or workplaces.

Remedy: Community Empowerment: An effective remedy begins with widespread education and training in a proven system of wise leadership, community organization, team building, and negotiation. With this purpose we have created a 5G Dojo to support local communities around the world that are facing similar challenges. The key is to share negotiation successes and practical experience, so these lessons can be immediately deployed within the network. Equally essential is to fortify community-wide resilience rapidly and effectively. (See: 5 Minutes toResilience)

Our Funding Goal: $ 100,000

Donations: Please make your check or money order payable to National Institute for Science, Law, and Public Policy, designated for "SAFE G/Community Empowerment Initiative". You can contribute in two ways.

o   Simple donation with full tax deduction.

o   Partial tax deduction (at cost) with benefits. Please see benefit levels below.

Sponsors: Please contact us to discuss any questions or concerns and customized donation options.

Springs of Amethysts - $100

  • Public Recognition as a Community Health Charter Sponsor
  • Signed copy of Julian Gresser, Piloting through Chaos—Wise Leadership/Effective Negotiation for the 21st Century (1995)
  • Free gift of the 5 Minutes to Resilience web app


Rivulets of Moonstones - $500

  • All of the above awards plus:
  • 5 Free Copies of 5 Minutes to Resilience App
  • 5 Free Copies of My Personal Resilience Journey/The Resilient Negotiator/Realizing Your Passion/Advancing Your Cause online courses


Sparkles of Opal - $1K

  • All of the above awards plus:
  • Public Lecture in Your Honor
  • 10 Free Copies of 5 Minutes to Resilience App
  • 10 Free Copies of My Personal Resilience Journey/The Resilient Negotiator/Realizing Your Passion/Advancing Your Cause online courses


Fountains of Pearls - $5K

  • All of the above awards plus:
  • ½ day workshop training and consultation with any organization or company


Jade Eddies - $10K

  • All of the above awards (except memberships) plus:
  • Two ½ day workshop, training and consultation with any organization or company of your choice
  • 20 Free Copies of 5 Minutes to Resilience App
  • 20 Free Copies of My Personal Resilience Journey/The Resilient Negotiator/Realizing Your Passion/Advancing Your Cause online courses


Sapphire Brooks of Laughing Hearts - $25K

  • All of the above awards plus:
  • 1 day of professional consultation and meetings


Ruby Streams of Laughing Hearts - $35K

  • All of the above awards (except memberships) plus:
  • One full day training program with materials for organization of choice to you.
  • 50 Free Copies of 5 Minutes to Resilience App
  • 50 Free Copies of My Personal Resilience Journey/The Resilient Negotiator/Realizing Your Passion/Advancing Your Cause online courses


Emerald Rivers of Laughing Hearts - $50K

  • All of the above awards plus:
  • Two full day training programs with materials for organizations of your choice
  • 100 Free Copies of 5 Minutes to Resilience App
  • 100 Free Copies of My Personal Resilience Journey/The Resilient Negotiator/Realizing Your Passion/Advancing Your Cause online courses


Diamond Rivers of Laughing Hearts - $100K

  • All of the above awards plus:
  • Four full day training programs with materials for organizations of your choice.
  • 200 Free Copies of 5 Minutes to Resilience App
  • 200 Free Copies of My Personal Resilience Journey/The Resilient Negotiator/Realizing Your Passion/Advancing Your Cause online courses

Mitochondrial Resilience

Mitochondria can shape the major stress-response pathways, thereby recalibrating the multi-systemic response to psychological stress.

In order to be successfully adaptive, organisms mount integrated stress responses across multiple organ systems. The ability to mount appropriate responses to psychological stress is critical for survival, and is thus considered a driver of species evolution. Maladaptive stress response in humans results in chronic stress characterized by specific symptoms, and which ultimately contributes to disease.

“Stressful experiences, on their own, do not cause damage or disease,” the authors write. “Rather, it is the organism’s responses to stress that have the potential to result in physiological dysregulation and dysfunction, culminating in allostatic load and disease. Our study demonstrates how mitochondria can shape the major stress-response pathways, thereby recalibrating the multisystemic response to psychological stress.”

Notes:

 

Next: Resilience and Epigenesis

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